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Karthik Chandramouli

Head of Business Development & Industry Solutions

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From Fee-for-Service Waste to Value-Based Efficiency: Rethinking Pharmacy in the VBC Era

The shift to Value-Based Care (VBC) models represents healthcare's most significant economic transformation in decades. Yet one critical aspect remains stubbornly anchored in fee-for-service thinking: pharmacy operations.

This blind spot creates a painful contradiction for healthcare systems and provider groups that operate under both fee-for-service and value-based payment models. The same decision that maximizes revenue under fee-for-service could significantly increase medical loss ratios under risk-based contracts.

The Value-Based Pharmacy Paradigm Shift

Traditional pharmacy operations focus on inventory management, dispensing efficiency, and maximizing reimbursement. Value-based pharmacy demands an entirely different approach:

  • Cost optimization vs. revenue maximization: Selecting the lowest-cost, therapeutically equivalent treatment option for at-risk patients
  • Site-of-service optimization: Evaluating home infusion vs. outpatient settings, based on total cost of care
  • Medication adherence: Prioritizing interventions that improve adherence and reduce downstream costs
  • Risk-stratified approaches: Applying different pharmacy protocols based on patient risk status
  • Integrated decision support: Embedding these insights at the point of care

One health system embracing this shift implemented a Bookend AI pharmacy operations solution that could distinguish between fee-for-service and value-based patients at the point of care, applying different optimization criteria based on risk status.

Case Study: Same Patient, Different Economics

Consider an actual case from this health system involving a Medicare patient requiring trastuzumab (Herceptin) treatment:

Before Bookend AI:

  • Prescribed: Ogivri (a biosimilar)
  • Cost: $2,500 per treatment
  • Approach: Standard treatment protocol for all patients, regardless of risk arrangement

After Bookend AI:

  • Prescribed: Trazimera (a Herceptin biosimilar in the same drug class)
  • Cost: $1,300 per treatment
  • Approach: Bookend AI identified that the patient was attributed to a full-risk contract and recommended the clinically equivalent, lowest-cost treatment option
  • Result: 48% cost reduction ($1,200 savings per infusion)

Multiplied across thousands of high-cost medication decisions annually, this type of optimization yielded projected savings of $5 million annually – with no reduction in clinical outcomes.

Aligning with Value-Based Care Quality Metrics

Beyond pure cost considerations, the value-based pharmacy approach directly supports key quality metrics driving VBC performance:

  1. Medication adherence metrics: By selecting medications with favorable cost-sharing for patients, adherence improved 5-8%
  2. Patient satisfaction scores: Reduced authorization delays and coverage issues improved patient experience measures
  3. Total cost of care: Lower medication costs directly impact the most significant component of medical cost ratios
  4. Hospital utilization: Fewer medication discontinuations led to reduced adverse events and hospitalizations

Bridging the Fee-for-Service and VBC Worlds

The optimization challenges for healthcare providers operating under both reimbursement models are especially acute. The Bookend AI solution deployed by this health system solves multiple problems at once:

  • Identify patient risk status and insurance plan in real-time
  • Apply tailored optimization based on full-risk or other contract status
  • Display cost impact for at-risk patients, or margin impact for fee-for-service patients
  • Recommend the optimal choice for each scenario

Pharmacy as a Strategic Value-Based Care Asset

As VBC continues to expand, pharmacy operations must quickly evolve from a tactical function to a strategic decision support role. Organizations leading in this Value-Based Pharmacy transformation are taking several key steps:

  1. Data integration: Combining clinical, claims, and pharmacy data for comprehensive decision support
  2. Proactive cost prediction: Flagging high-cost medication opportunities before prescribing
  3. Real-time guidance: Embedding insights at the moment of prescribing
  4. Learning systems: Continuously updating recommendations based on payer outcomes and changing economics
  5. Patient engagement: Involving patients in shared decision making on the rationale for specific medication choices

The Future of Value-Based Pharmacy

This health system's experience provides a glimpse into the future of pharmacy operations in a value-based world – one where medication decisions incorporate not just clinical factors, but also economic considerations aligned with the total cost of care.

For healthcare organizations navigating the transition to value-based care, reimagining pharmacy operations represents one of the most immediate, high-impact opportunities to align clinical practice with financial incentives – and AI-powered decision support at the point of care is proving to be the key enabler of this transformation.